General Information

  • ID:  hor001189
  • Uniprot ID:  A8WRQ7
  • Protein name:  FMRFamide-like peptide
  • Gene name:  flp-2
  • Organism:  Caenorhabditis briggsae
  • Family:  FMRFamide related peptide family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  SPREPIRF
  • Length:  8
  • Propeptide:  MQASAILSALFLVLLAVIGTTVAQSNDNQLGVFEASMMAKRLRGEPIRFGKRSPREPIRFGKRFNPLPDYDFQ
  • Signal peptide:  MQASAILSALFLVLLAVIGTTVA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A8WRQ7-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor001189_AF2.pdbhor001189_ESM.pdb

Physical Information

Mass: 112617 Formula: C45H72N14O12
Absent amino acids: ACDGHKLMNQTVWY Common amino acids: PR
pI: 10.4 Basic residues: 2
Polar residues: 1 Hydrophobic residues: 2
Hydrophobicity: -115 Boman Index: -3215
Half-Life: 1.9 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 48.75
Instability Index: 7832.5 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  18760316
  • Title:  Comparative Peptidomics of Caenorhabditis Elegans Versus C. Briggsae by LC-MALDI-TOF MS